Cannabis has a long history of medical use as an analgesic and antispasmodic agent. Cannabis also shows some promise as an anti-inflammatory agent, an anti-anxiety agent, a chemotherapy agent, a migraine treatment agent, a muscle relaxant and as a neuroprotective agent 25, 51. However, it also shows some effects that are more specific to certain clinical disorders, such as appetite stimulation and weight loss. This is one of the main reasons why people love to buy the lavender hemp salve products
In addition, some research suggests that cannabis has some effects that appear to be more effective and potent than those of certain currently used medications. If you are interested, you can get help with your marijuana, so that you fully understand all of its benefit.
It is possible that these effects are related to a multitude of effects including the stimulation of the endocannabinoid system, the reduction of inflammation and the induction of apoptosis 54. Many of these phenomena may occur via cannabinoid receptors. The cannabinoid receptors, also known as cannabinoid 1 receptor (CB 1 R), are a family of G protein-coupled receptor that has been described for a variety of cells and organ systems. The main members of this family of receptors are CB 1 R and CB 2 R, but there are also CB 1 and CB 2 R knockout receptors 54,55. CB 1 R is the most abundant of the CB receptors and is expressed predominantly in the central nervous system and immune system, especially of peripheral tissues (for a review see http://www.ncbi.nlm.nih.gov/pubmed/11843623). CB 1 R is expressed as a membrane protein and is expressed at low levels in the brain and peripheral tissues and in the periphery in particular in the lung and lymphoid tissues, among others. A characteristic of the CB 1 receptor is its “high” affinity for cannabinoid and endogenous cannabinoid ligands. These ligands bind to a group of low-dimensional proteins on the surface of the cell membrane, where the ligand binding is initiated by intracellular calcium signaling and by phospholipase A 2, leading to the phosphorylation of proteins involved in a variety of cellular functions such as the activation of ERK and the phosphorylation of Akt.
In human cells, CB 1 R is expressed in the hippocampus, the cerebellum, the cortex, the pituitary, the medulla, the pituitary gland, and the thalamus. In brain slices, CB 1 R is also expressed in the striatum, nucleus accumbens, and the frontal cortex. At least three different CB 1 R knockout mouse lines have been developed to study the role of CB 1 R in the CNS. These mice are very similar in size and behavior to wild-type mice, but they lack the CB 1 R protein, and all are deficient in several neuropsychiatric phenotypes. In this study we have analyzed these three mouse lines in a rat model of PTSD.